Human growth hormones in excessive amounts can negatively impact your health. For example, people think that HGH can be deficient for your kidneys and negatively impact their functioning. But the question is, is HGH bad for your kidney? Read more to find out.
The connection between HGH supplements and kidney health is a bit of a complicated one. On one hand, children with kidney problems need to rely on the supplementation of HGH injections.
Yet, on the other hand, the supplement may also cause unsavory side effects in them. A number of studies have shown that children who suffer from a lack of healthy amounts of human growth hormones tend to develop problems in their renal functions.
You don’t need to worry if your HGH is sufficient. But any spike, or any dip in its supply both have unfavorable effects on the normal function of your kidney.
No study deduces that HGH brings adverse effects on renal functions. In contrast, an article published on the Health Gains website mentions the opposite effect.
A landmark clinical trial established that HGH replacement therapy improves treatment adherence during kidney dialysis.
The kidney is especially susceptible because it is the organ that filters blood.
In addition, HGH can also cause an increase in blood pressure, which can put extra strain on the kidneys. This is particularly concerning for children with pre-existing kidney problems, as their kidneys may already be functioning at a reduced capacity.
HGH therapy is also associated with fluid retention, which is a common side effect. Normally, the kidneys filter waste and excess fluids from the bloodstream, which are then expelled as urine.
However, if there is an excess of fluids in the body, the kidneys must work harder to eliminate them. This can cause harm to the kidney tissue and impair its function over time due to the increased workload.
Furthermore, fluid retention may result in tissue swelling, including in the kidneys, which can put pressure on small blood vessels and hinder their ability to filter waste products efficiently.
The slowdown in the pace at which the kidney excretes wastes from the body and purifies blood causes changes in the kidney size.
When you take excessive HGH doses, it impacts the kidney function by increasing the flow of renal plasma, and the rate of glomerular filtration rate.
But when the GH level subsides, the filtration and speed at which fluids flow into the kidney also slows down.
Per an article on the PubMed Advanced User Guide publication, these changes occur between 5 to 23 hours after injecting the HGH.
Also, HGH therapy has been associated with an increased risk of kidney stones. This is because high levels of growth hormone can cause an increase in calcium excretion in the urine.
High levels of growth hormone can stimulate the production of calcitriol, a hormone that increases calcium absorption in the intestines and kidneys.
This can lead to higher levels of calcium in the urine, which can increase the likelihood of kidney stone formation.
Another potential negative effect of HGH therapy on people with kidney problems is that it can worsen pre-existing kidney disease. HGH therapy can increase the metabolic demands on the kidneys, which can further strain already compromised kidney function.
This can result in increased proteinuria (protein in the urine), reduced glomerular filtration rate (GFR), and ultimately, progression of kidney disease.
Therefore, children with pre-existing kidney disease who are considering HGH therapy should be carefully evaluated by a healthcare professional to assess the potential risks and benefits of treatment.
Furthermore, there is a risk that HGH supplementation can lead to the development of a condition known as acromegaly, which is characterized by the abnormal growth of bones and soft tissues.
This can put additional strain on the kidneys and may lead to kidney damage or failure over time.
However, it is not only children with HGH deficiency who face this kind of difficult problem. Children who have an overproduction of HGH also face problems such as acromegaly.
When this condition develops, the kidney typically gets enlarged as well, and then additional health problems may appear. Health problems typical to the enlarged kidneys may include extra urine retention.
It has been suggested that regular HGH therapy has the ability to reduce kidney problems in children with HGH deficiency. This is because HGH therapy can help to normalize the levels of growth hormone in the body, which can prevent the development of renal problems.
Studies then also show that children who undertake HGH therapy have better development of the kidney alongside their close-to-normal height growth.
However, the negative side effects of taking the HGH injections also include the children’s sensitivity to taking kidney implants. There are suggestions that claim the children typically develop resistance to receiving kidney implant.
This resistance can occur because HGH therapy can cause changes in the immune system that may make it more difficult for the body to accept a foreign organ.
In addition, the increased growth hormone in the body can lead to the growth of abnormal tissues in the kidney, which can further complicate any future kidney transplant.
Also a study published in the Journal of Clinical Endocrinology and Metabolism found that adults who received HGH therapy during childhood were more likely to have reduced kidney function and other markers of kidney disease.
This may be problematic if the children eventually grow up and may need a kidney transplant later on in life.
It is important for medical professionals to closely monitor children who receive HGH therapy for any signs of kidney problems or other complications.
Regular kidney function tests and careful monitoring of HLA antibodies can help to detect any issues early and ensure that appropriate treatments are provided.
The IGF-1 has a direct impact on the rate at which the kidney filters fluids and the plasma uptake.
Hence any increase in the glomerular filtration rate GFR and renal plasma factors RPF can cause renal hypotrophy.
This means that the kidney has to work overtime to discharge its elevated workload. Subsequently, as per an article on the PubMed Advanced User Guide publication, the increased GH level in the kidney could trigger glomerular sclerosis.
Yet, even with all that said, there is a lack of definitive research on the correlation between HGH injections and renal functions. While some studies have suggested that HGH injections may have negative effects on the kidneys, others have found no significant impact.
That means studies about the definitive correlation between HGH injections and renal functions are lacking. Researchers are still carrying tests to see if HGH really has negative or positive effects on HGH.
In the present state, opinions still vary and to find a more solid answer every patient will need an individualized examination by their health care provider.
SIMILAR QUESTION
Does Growth Hormone Help Kidney Disease?
Kidney disease is a serious and debilitating condition which affects millions of people around the world. Kidney disease can be caused by a variety of factors, including diabetes, high blood pressure, and genetics. As the kidneys are responsible for the important function of filtering toxins and waste from the body, damage to the kidneys can cause a variety of health issues. Fortunately, there are treatments available which can help to slow the progression of kidney disease, and in some cases, even reverse it. One potential treatment for kidney disease is the use of growth hormone.
Growth hormone is a hormone produced naturally in the body which is responsible for promoting growth and development of the body’s tissues, including the kidneys. Growth hormone is also known to have an effect on kidney function, and it is thought that increasing the amount of growth hormone in the body may be an effective treatment for kidney disease.
Several studies have been conducted which have looked at the potential benefits of using growth hormone to treat kidney disease. One study, published in the journal Kidney International, found that growth hormone therapy was associated with improved kidney function in patients with chronic kidney disease. The researchers concluded that growth hormone therapy may be beneficial for patients with chronic kidney disease, as it may improve kidney function and slow the progression of the disease.
Another study, published in the journal Clinical Kidney Journal, looked at the effects of growth hormone on kidney function in patients with end-stage renal disease. The results of this study showed that growth hormone therapy was associated with improved blood flow to the kidneys and a decrease in creatinine levels, which are markers of kidney damage. The researchers concluded that growth hormone therapy may be a useful treatment for patients with end-stage renal disease.
Although there is evidence to suggest that growth hormone therapy may be beneficial for patients with kidney disease, more research is needed before it can be recommended as a treatment option. Furthermore, it is important to remember that growth hormone therapy is not without its risks. Growth hormone therapy can cause side effects, and there is a potential for long-term health complications. Therefore, it is important to speak with your doctor before considering growth hormone therapy.
In conclusion, there is evidence to suggest that growth hormone therapy may be beneficial for patients with kidney disease. However, more research is needed to fully understand the potential benefits and risks associated with this treatment. It is important to speak with your doctor before considering growth hormone therapy in order to ensure that it is the right treatment option for you.
