Since Growth Hormone is a hormone and is released in your bloodstream, it is common to wonder if it has any effects on your blood pressure. But the question is, does growth hormone increase blood pressure?
Human Growth hormone (HGH) is essential for growth especially in children, but it also affects many other developments in the body as well, which include bone density, muscle mass, and mood.
Different hormones control different body functions, including growth, metabolism, sexual function and mood.
Growth hormone levels do not remain constant and it can change throughout the day, and physical activity plays a part in it. Even a small change in the HGH level affects the functioning of the body.
Too low and too much HGH levels can equally have adverse effects on the human body.
Low HGH is directly related to short stature, anxiety, weak muscles, and bone increased fat, weak heart increased risk of heart disease.
According to a report published in the Nature Journal, growth hormone (GH) is known to have positive effects on the heart. It can enhance cardiac function and reduce the risk of heart disease. Conversely, a deficiency in GH may result in changes to heart structure and function, potentially raising the risk of cardiovascular problems.
Similarly, high growth hormone levels can lead to muscle or joint pain, fluid retention and swelling, and high blood pressure. Human Growth Hormone is an important agent in cardiovascular physiology.
According to a study reported by Mayo Clinic, growth hormone (GH) can exert both direct and indirect influences on blood pressure. GH has the capacity to induce the constriction of blood vessels, potentially leading to an elevation in blood pressure. Furthermore, GH-induced alterations in the body’s fluid equilibrium, including increased fluid retention, can also be a contributing factor to elevated blood pressure.
Besides affecting the structure and contractibility of the heart, both HGH deficiency and excess are directly associated with heart problems.
Blood pressure problems especially high systolic BP was reported to be higher in Adult Growth Hormone Deficiency (AGHD) patients than in normal controls.
The clinical statistics associated with Growth Hormone excess or GH deficiency are known to be linked with an increased risk for cardiovascular disease and in some cases death as well, which suggests that either an excess or a deficiency in GH and/or IGF-I is harmful to the cardiovascular system.
But excess growth hormone excess usually causes a specific heart disease characterized by concentric cardiac hypertrophy associated with diastolic dysfunction and later systolic dysfunction, which can result in heart failure if growth hormone excess is not constrained.
In the case of excessive growth hormone, abnormalities of cardiac rhythm and anomalies of cardiac valves can also be experienced. Moreover, the most common risk involved with cardiovascular anomalies is high blood pressure (hypertension).
Growth harmonies can increase the amount of blood pumped by the heart (cardiac output) by stimulating the heart to beat faster and harder. An outcome of this could be a rise in blood pressure which may affect your health and well-being.
In addition, growth harmonies can stimulate the production of renin, an enzyme produced by the kidneys that convert angiotensinogen (a protein in the blood) to angiotensin I.
Angiotensin I is then converted to angiotensin II, a potent vasoconstrictor that can raise blood pressure.
Growth harmonies can activate the sympathetic nervous system, which can cause blood vessels to constrict and increase peripheral vascular resistance. This can lead to an increase in blood pressure.
Besides, growth harmonies can stimulate the kidneys to retain sodium, which can increase blood volume and contribute to an increase in blood pressure.
According to information provided in the MSD Manual, growth hormones have the ability to impact the kidneys, prompting them to retain sodium. This sodium retention, in turn, leads to the retention of water, resulting in an elevation in blood volume. This increased blood volume is a contributing factor to elevated blood pressure.
Growth harmonies can stimulate the production of endothelin-1, a peptide produced by the endothelium that can cause blood vessels to constrict. This can lead to an increase in peripheral vascular resistance and an increase in blood pressure.
Growth harmonies can increase the activity of the renin-angiotensin-aldosterone system in the kidneys, which can cause the kidneys to retain sodium and fluid. This can increase blood volume and contribute to an increase in blood pressure.
Apart from that, growth harmonies can stimulate the adrenal glands to produce cortisol, a hormone that can cause blood vessels to constrict and increase peripheral vascular resistance.
Cortisol can also stimulate the kidneys to retain sodium and fluid, which can contribute to an increase in blood pressure.
Also, HGH decreases the production of nitric oxide which is a molecule that dilates blood vessels and decreases blood pressure.
HGH can decrease the production of nitric oxide by decreasing the expression of the gene that codes for the enzyme responsible for its production. This can cause an increase in blood pressure by reducing vasodilation.
HGH increases arterial wall thickness and stiffness. HGH can stimulate the production of collagen and other extracellular matrix proteins that make up the arterial walls. This can increase their thickness and stiffness, which can lead to an increase in blood pressure.
Furthermore, HGH increases the production of pro-inflammatory cytokines. Cytokines are a class of proteins that play a vital role in modulating the immune response and inflammation within the body.
HGH can stimulate the production of pro-inflammatory cytokines such as interleukin-6 and tumor necrosis factor-alpha. These cytokines can cause endothelial dysfunction and contribute to hypertension.
Also, HGH increases the production of reactive oxygen species. Reactive oxygen species (ROS) are molecules that can damage cells and tissues in the body.
HGH can increase the production of ROS by increasing the activity of enzymes that generate them. As a consequence, this can harm the blood vessels and contribute to the development of hypertension.
SIMILAR QUESTION
Does Growth Hormone Affect Your Heart?
Introduction
Growth hormone (GH) is a protein hormone produced in the pituitary gland located at the base of the brain. It is responsible for the growth and development of the body. It also plays a role in many other body functions, including metabolism and heart health. This paper will discuss how GH affects the heart and how it can be beneficial to heart health.
What is Growth Hormone?
GH is a hormone produced by the pituitary gland located in the brain. It is responsible for stimulating growth and development in children and adolescents. In adults, it helps to regulate metabolism, body composition, and energy levels. GH has also been linked to heart health, as it helps to regulate the way the body utilizes and stores energy.
How Does Growth Hormone Affect the Heart?
GH has been linked to a number of heart health benefits. It can help to lower cholesterol, increase HDL (good cholesterol) and decrease LDL (bad cholesterol). Additionally, GH helps to reduce inflammation in the body, which can help to reduce the risk of heart disease. GH also helps to regulate blood pressure, which is beneficial for maintaining a healthy heart.
In addition, GH helps to regulate the body’s metabolism, which is important for maintaining heart health. GH can help to increase the body’s ability to burn fat and use it as fuel, which can help to reduce the risk of obesity and heart disease. GH can also help to increase the body’s sensitivity to insulin, which is important for controlling blood sugar levels and reducing the risk of diabetes and heart disease.
Conclusion
In conclusion, GH is a hormone produced in the brain that plays a role in many body functions, including heart health. GH helps to lower cholesterol, reduce inflammation, regulate blood pressure, and increase metabolism. All of these effects can help to reduce the risk of heart disease and maintain a healthy heart.
