Growth hormone usually referred as GH is a peptide hormone that is built of protein. Its main function is the growth stimulation, reproduction and regeneration of cells in human beings and also other animals. The Growth hormone is single-chain polypeptide, 191-amino acid, which is secreted, synthesized and stored by Somatotroph cells that are situated in the anterior part of pituitary gland.
Somatotropin is a growth hormone that is developed naturally in animals; on the other hand, the term Somatropin is the growth hormone formed by a recombinant DNA technology and is generally abbreviated as "HGH" or Human Growth Hormone in humans. It is the recommended drug in medicine for treating growth disorders in children and growth hormone deficiency in adults.
The Human Growth Hormone which can also be called as Somatrophin is by and large found in kids and also young grown-ups at its maximum levels. The human body produces it naturally to stimulate growth during childhood phase and to maintain tissues and organs of the body throughout the whole life.
A small pea-sized structure that is situated at the bottom of the brain is called as pituitary gland. This gland produces largest quantity of Human growth Hormone. This pituitary gland slowly decreases the amount of production of hormone as the age advances. It is known to be one of the major protein or hormone produced by pituitary gland.
The role of HGH:
The Human Growth Hormone has several significant roles such as:
- Converts body fat into muscle mass
- Elevates energy level
- Enhances tissue growth
- Repairs the tissues
- Helps in cell replacement
- Brain and sexual function
- Production of enzymes
- Heals the body
- Strengthens the bones
- Integrity of vital body parts
In 1996 scientists isolated this hormone for the first time. It was used for the treatments in the children who suffered from problems such as stunted growth. The only source of the Human Growth Hormone production was from human cadavers before the advancement of genetic engineering. Then, the pituitary glands were removed from dead body of human and these glands were processed and were made available as injectable forms.
Uses of HGH:
The Human Growth Hormone drug is generally useful for dwarf children, but now-a-days various other uses can be found. Sportsman and athletes have started to use this to help in boosting their performances in different sports. The most important use of HGH is in increasing muscle size. It also helps in recovering the tired muscles rapidly.
It is also useful in:
- Treatment of Growth Hormone Deficiency, especially in children
- Weight Loss
- The short Stature Caused due to Turner's syndrome and Prader-Willi Syndrome
- Treatment of Rheumatoid Arthritis in children
- The Improper Growth of Children suffering from Renal Disease
- Short Stature arising due Short Bowel Syndrome or due to unknown causes
- Osteoporosis Treatment
Some general signs of Growth Hormone deficiency are poor growth, a chubby stature and an immature face. Children with this deficiency may also experience low blood sugar known as hypoglycemia and seizures. In adults, this deficiency causes decreased bone and muscle density and reduction in energy. It is also responsible for obesity.